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The ongoing development and increased availability of DNA sequencing technology have uncovered several molecular causes of SLOCA besides spastic paraplegia type 7 and very late-onset Friedreich ataxia

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The peptide acts as a signalling molecule that communicates with cells, telling them to repair, regenerate, and produce essential proteins

Early BBB breakdown and subacute inflammasome activation and pyroptosis as a result of cerebral venous thrombosis

DSIP significantly increased the rate of phosphorylated respiration (V3), which represents the maximal oxygen consumption rate in the presence of ADP