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After synthesis, the material undergoes purification through high-performance liquid chromatography (HPLC) , followed by mass spectrometry (MS) verification

1 The drugs approved for this purpose include disulfiram (aldehyde dehydrogenase inhibitor), naltrexone (opioid receptor antagonist), acamprosate (various sites of action), and nalmefene (opioid receptor modulator)

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However, patients and healthcare providers increasingly ask about kidney-related safety, particularly during extended treatment periods

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