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Various factors can deplete these amino acids or impair your body's ability to produce sufficient glutathione, making supplementation a practical approach to maintaining optimal levels

10.1113/jp275230 44 SeferovicM

As reported, ROS generates hydrogen peroxide, which is a harmful molecule that can be scavenged by the glutathione peroxidase through GSH, it is found in the cytosol and the mitochondria, and by the catalase which is present in the peroxisomes

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Trigonelline recovers memory function in Alzheimers disease model mice: evidence of brain penetration and target molecule