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TNF-alpha mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimers beta-amyloid oligomers in mice and monkeys

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The restoration of first-phase insulin response is a well-established observation caused by weight loss in type 2 diabetes [29]

It is a hormone produced by our body with numerous metabolic effects like stimulating the secretion of insulin , delaying gastric emptying , suppressing glucagon release , and signaling to the brain feelings of fullness

Binge-like palatable food intake in rats reduces preproglucagon in the nucleus tractus solitarius