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In rats with experimental AIT, after the use of selenium yeast dietary supplement, in addition to a decrease in the levels of TgAb, TPOAb and a decrease in B-cell-activating factor (BAFF) in the blood serum, the expression of IL-10 in the thyroid tissue increased, the number of Breg in the spleen increased, and also decreased TSH level (77)

but this was not driven by any single study, again adding to the argument that between subjects' variation may contribute to the dispersion of the mean effect in MRS studies of ACC GSH

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