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Animal Studies Administration of IGF-1 LR3 to rodents produces dose-dependent increases in body weight and lean body mass, with the weight gain being primarily accounted for by increases in skeletal muscle mass rather than fat accumulation

These weight reductions continued to improve at 36 weeks, with all doses achieving body weight reductions ranging from 9.4% (21.6 lb

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Nonetheless, our case series also has notable strengths

While the actual numbers reported with these "serious" medical side effects are small and not currently substantiated, these reports have caused a media frenzy