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An example of this effect can be observed with bradykinin (purple box within Figure 8 ) (347, 348), and preload failure experienced in ME/CFS may be correlated with the endogenous vasodilator substances produced in skeletal muscles

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Understanding these effects helps patients distinguish between expected medication responses and symptoms requiring medical evaluation

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[PubMed] [Google Scholar] Huang C-S, Chang L-S, et al

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