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This typically means switching to a stronger medication or making dietary or exercise changes, although these measures do not always resolve the plateau

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Pull-down assays Immobilized His-USP14 was obtained as described above in Expression and purification of 6His-USP14 protein in E

Patients with MS often experience comorbidities including metabolic syndrome, type 2 diabetes, and obesity, which may be exacerbated by reduced mobility and certain treatments, particularly corticosteroids used for acute relapses