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However, decreased responsiveness to VIM DBS by select body parts (possibly due to the somatotopic organization of the VIM nucleus) increased tolerance to VIM stimulation due to compensation or disease progression [176, 177], and the development of adverse side effects, such as dysarthia and dysphagia [174], in patients, has driven efforts to optimize DBS targeting
Additionally, healthy sunlight exposure may also help reduce autoimmunity and protect from neurological conditions such as Alzheimers and Parkinsons disease
For instance, PLGA polyester decomposes in the body to produce lactic acid and glycolic acid, allowing the encapsulated immune antigens to gradually release and achieve the effect of continuously stimulating the body's immune system
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