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Results: Based on the small intestinal transcriptome of geniposide, a recognized small-molecule GLP-1R agonist, we identified that cinchonine exerted GLP-1R agonist-like effects

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Moreover, the combination of differentiation and hypoxia induces even more oxidative stress, possibly because hypoxia induces mitochondrial ROS production and stimulates reductive carboxylation of glutamine, thereby increasing the NADPH demand 28,29

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