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Effective concentrations range from 0.5% to 2%

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[16] There is no advantage to the use of adenosylcobalamin or methylcobalamin forms for the treatment of vitamin B 12 deficiency

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Specific compatibility considerations include confirmation of absence of reducing agents for disulphide-containing peptides, BSA carrier supplementation for recombinant proteins, and acetic acid acidification for hydrophobic peptides requiring low pH solubilisation