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doi:10.1038/nn.2146

Conclusions The results from this study showed that blood GSSG, MDA, homocysteine, SAH, nitric oxide, and copper concentrations were significantly increased, whereas GSH, tGSH, GSH/GSSG, tGSH/GSSG, SAM/SAH, methionine, cysteine, vitamins (B9, B12, D, and E), and calcium concentrations were significantly reduced in children with ASD

These results indicate that the inhibition of mTOR is able to reduce immunosenescence which might explain the lifespan extension of mice with rapamycin therapy [18, 19]

Sloane RAS, White MG, Witt RG, Banerjee A, Davies MA , Han G, Burton E, Ajami N, Simon JM, Bernatchez C, Haydu LE, Tawbi HA, Gershenwald JE, Keung E, Ross M, McQuade J, Amaria RN, Wani K, Lazar AJ, Woodman SE, Wang L, Andrews MC, Wargo JA