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[1] According to the researchers TGF-beta1 induction of angiogenesis requires a rapid and transient apoptotic effect mediated by VEGF/VEGFR2. AHK-Cu, by enhancing levels of the Vascular Endothelial Growth Factor, may possibly activate fibroblasts and endothelial cells

Teubner (2005) Die ganze Welt der Vitamine, Mineralstoffe und Enzyme

As vitamin B12 seems to be better absorbed on an empty stomach (or better yet, acidic environment), you should try to wait for a few hours after having your evening meal before taking them

A B12 deficiency can also lead to health problems that can lead to major birth defects

caution in methylation disorders (use only under supervision) No known drug interactions with oral medications, but B12 may mask B9 (folate) deficiencycombined B-vitamin status should be assessed periodically