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Rev Cardiovasc Med 24(7):202

According to FDA prescribing information, these include nausea, vomiting, diarrhea, constipation, and abdominal pain

Both medications were initially developed to treat type 2 diabetes, but clinical results showing dramatic weight reductions sparked their evolution into tools for obesity management

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The inhibitory effect is presumably mediated indirectly through somatostatin secretion, but a direct effect cannot be completely excluded