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Common Side Effects Nausea or upset stomach Diarrhea or constipation Heartburn or indigestion Fatigue Most patients find that these side effects are strongest during the first few days after an injection or when they increase their dose

Support liver health: Adopting a liver-friendly diet, limiting alcohol intake, and maintaining a healthy body weight can support liver function and improve histamine metabolism

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Additional analysis was done to determine the proportion of the estimated treatment difference in HOMA2-IR with tirzepatide versus semaglutide that was attributable to an indirect association with body weight reduction

2008 Dec;56(12):2244-51