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Preclinical studies have shown a genetic deletion of antioxidant enzymes (e.g., SOD, GPx) inducing HTN in mice (Rodrigo et al., 2021)

These findings are in agreement with the earlier data indicating a transient increase of intracellular Zn levels in 3T3L1 cells at the transition from G0/G1- to S-phase of the cell cycle, followed by a decline to the initial levels

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GLP-1 medication alone bone density declined at the hip and spine Exercise alone bone density was preserved while still losing weight GLP-1 medication plus exercise greatest weight loss AND preserved bone density The takeaway: exercise isnt optional when youre on these medications its preventive

doi: 10.1002/ana.22230 120 MagliozziRHowellOVoraASerafiniBNicholasRPuopoloMet al