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The SURMOUNT-1 clinical trial, which tested tirzepatide for weight loss in adults without diabetes, found that musculoskeletal complaints like back pain, arthralgia, and myalgia did not occur at significantly higher rates in the tirzepatide group compared to placebo

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Despite increasing prevalence estimates, the etiology and pathophysiology of ASD remain incompletely understood, and there are no established diagnostic biomarkerssupporting the rationale for metabolomic profiling and diet-responsive biomarker discovery

The study findings suggest a possible link between semaglutide use and an increased risk of NAION in patients with diabetes

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