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Increased levels of NAPQI reduce the ability to detoxify a host of toxic chemicals in the environment, increasing oxidative stress, which leads to protein, lipid, and nucleic acid damage from free radicals

The first conditional recommendation advises the use of GLP-1 drugs by adults, except pregnant women, for long-term obesity treatment, while the second suggests interventions like a healthy diet and physical activity to be offered alongside the medicines

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A food constituent of particular interest is folate-binding protein (FBP) occurring in milk

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