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The mechanism involves modulation of dopamine and serotonin systems alongside promotion of nerve growth factor

In a 12-week randomized clinical trial involving 300 obese adults, participants receiving 1 mg daily of AOD-9604 lost an average of 2.6 kg (approximately 5.7 pounds) compared to 0.8 kg (1.8 pounds) in the placebo group

That is the proposed reason it does not raise IGF-1 levels or impair insulin sensitivity in animal work, in contrast to full-length growth hormone

Researchers are calling for larger, well-designed randomized controlled trials in humans to determine whether these impressive animal results translate to clinical practice