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It compared 132,551 individuals who were prescribed a GLP-1 medication to help manage type 2 diabetes with 201,136 who were prescribed sulfonylureas, another type of medication for diabetes

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(2) Specific binding of low-affinity ligands to receptors usually requires high or even supersaturated concentrations to ensure effective recognition

We therefore generated new cohorts of mice lacking Gipr in the hypothalamus (Gipr hypo-KO ), by targeted injection of AAV-Cre or control AAVGFP (Gipr hypo-GFP ) into the paraventricular nucleus (PVN) (Fig

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