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No studies have assessed effects of extended use on cancer development risk, fertility, or interaction profiles with common medications in human populations

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These abnormalities were previously regarded as secondary epiphenomena of metabolic dysfunction, but accumulating evidence now indicates that they arise from hyperglycaemia-driven OCTN2 impairment, insulin resistance, and oxidative stress, together forming a distinct carnitine-related metabolic signature

Biotechnol Lett 35(12):21132119