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In vitro models show it enhances superoxide dismutase activity for antioxidant effects and stimulates metalloproteinases for matrix turnover

12 Conversely, non-RBD-PD may reflect a brain-first subtype, in which pathological -synuclein originates within the central nervous system and then spreads peripherally

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It is a hypothesis-generating screen, powerful for prioritizing what to study next, but it does not measure a clinical outcome

Some GLP-1 medications are approved for certain adolescents with obesity, but microdosing and weight loss strategies in teens are not standard care