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The takeaway

While uncommon, some studies suggest NAION may occur slightly more often in people taking GLP-1 medications

Session 1 After informed consent was obtained, participants completed a Timeline Follow Back (TLFB) to measure drinking in the past 30 days, Patient Health Questionnaire (PHQ-9), and a medical interview which asked about current and past medication history and other medical history to ensure safe participation in the study, as reviewed by a study physician

Our initial attempts to crystallize the engineered full-length GLP-1R in complex with PF-06372222 (a previously used negative allosteric modulator for crystallization of the isolated TMD) did not yield any crystal

The Chinese approval path for HRS-7535 looks increasingly clear after primary endpoints were met in two pivotal trials, offering Hengrui a significant first-mover advantage for oral obesity treatments in China