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Several studies are under way to assess the effects GLP-1 agonists may have on people with pre-existing mental health conditions

AHA Journals+1 A new twist: statins, the microbiome, bile acids and lower GLP-1 In 2024, a high-quality translational study reported that statins can aggravate insulin resistance by reducing circulating active GLP-1 levels and that the effect appears to be microbiome-dependent

Most people experience improvement within 68 weeks at a stable dose

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Ive written extensively on both Milk Thistle and L-carnitine, linked below, and I encourage you to give them a read if they are a topic of interest