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Ig Sanita Pubbl 80(4):130134 Garcia-Bello JA, Gmez-Daz RA, Contreras-Rodrguez A, Talavera JO et al (2014) Carotid intima media thickness, oxidative stress, and inflammation in children with chronic kidney disease

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International Journal of Clinical Practice, 75 (11), e14469

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5.4 Polyphenols Mitochondria are the primary site for the creation of free radicals due to the production of adenosine triphosphate (ATP) through oxidative phosphorylation (OXPHOS), so elevated oxidative stress in individuals with DS primarily affects these organelles