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This has led some researchers and clinicians to explore whether higher doses might be more appropriate for people with severe obesity

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Instead of escalating every 4 weeks, increases happen every 6-8 weeks in smaller increments (1.0-1.5 mg instead of 2.5 mg)

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Beyond the gut, people who took GLP-1 medications were also more likely to be diagnosed with problems in their bones and joints, like arthritis and tendinitis, compared with people taking other medications to manage their blood sugar