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This newborn screening (NBS) uses absolute measurements and ratios of acylcarnitine levels in dried bloodspots to identify conditions that result in an imbalance in (acyl)carnitine blood levels

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Potential patients for any planned clinical trials may not be adequately diagnosed or identified with the diseases which we are targeting or may not meet the entry criteria for such trials

This, in itself, is an almost completely insoluble, hydrophobic compound, but with bile acids and phospholipids it is able to exist in a clear, single-phase solution in the bile

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