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In a population-based study of 3884 elderly people, deficiency of vitamin B 12 was associated with almost 70% more likelihood of having a depressive disorder.54 In another cross-sectional study of 700 community-dwelling, physically disabled women aged 65 years, vitamin B 12 deficient women were twice more likely to have severe depressive symptoms.55 Although controlled studies to show response to vitamin B 12 replacement therapy in depression are lacking, it is recommended that all patients with vitamin B 12 deficiency should be managed as part of depression treatment

These effects can include fatigue and weakness, numbness and tingling in the hands and feet, and memory loss and cognitive decline

Data from the in-trial period

Weeks 48: The This Is Working Phase If youve stayed consistent, this is where many clients feel like theyve hit a groove

I have a connective tissue disorder and have dealt with significant pain daily for five months