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How GLP-1 Therapy May Influence Testosterone and Sperm GLP-1 receptor agonists, including semaglutide (Ozempic, Wegovy) and liraglutide (Saxenda, Victoza), are widely used to treat type 2 diabetes and obesity

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This finding was consistent for cardiovascular mortality (HR 0.90, 95% CI from 0.50 to 1.61) and all-cause mortality (HR 0.80, 95% CI from 0.51 to 1.25)

Tirzepatide has anecdotally been associated with reduced alcohol cravings in some users, but if a person with alcohol use disorder stops drinking suddenly while on bupropion, the withdrawal period combined with the lowered seizure threshold creates a genuinely dangerous situation