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After this 1:1 matching, the final study population included 57,456 participants, with 28,728 individuals in each treatment group

An additional 202 articles were excluded for the following reasons: irrelevant study population (n=60), unrelated interventions (n=90), insufficient or incomplete data (n=52), and language limitations (non-English)

This loop significantly amplifies renal sympathetic nerve activity and exacerbates sympathetic hyperactivity (Wang et al., 2024), providing a novel mechanism for aging-related cardiac dysfunction

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