Research continues to explore the broader therapeutic potential of GLP-1, including its effects on the cardiovascular system, brain function, and its potential role in the treatment of conditions beyond type 2 diabetes, such as Parkinson's disease and Alzheimer's disease
doi: 10.1038/s41591-025-03774-9 182 GruberTLechnerFKriegerJPGarca-CceresC
We did not observe any age-associated differences in GLP-1 M responsiveness in male subjects
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The recent data provide evidence that GLP-1R activation affects the mechanisms of signal transduction associated with insulin resistance, energy homeostasis of the brain, neurogenesis, synaptic functioning, neuroinflammation and other cell responses to stress, pathological protein aggregates, proteostasis, the cerebrovascular system, and the BBB [42]
