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Oxidative stress and blood-brain barrier dysfunction under particular consideration of matrix metalloproteinases

Contact your healthcare provider promptly if you experience: Repeated or persistent vomiting An inability to keep food or fluids down Dizziness, reduced urination, or very dark urine Severe or persistent abdominal pain Abdominal pain that radiates toward the back Significant abdominal swelling Severe constipation An inability to pass stool or gas Worsening nausea or diarrhea Symptoms that make it difficult to eat or drink Digestive symptoms that continue despite meal adjustments Vomiting and diarrhea can lead to dehydration

Consistently eating large meals raises the nausea rate from about 22% to 41% based on clinical observations

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