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The toxic effects of HT on HCT116 and SW480 cells were diminished by the co-administration of Fer-1 and HT (Fig

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glutathione's antioxidant activity may dampen this response Mechanism 4: Thyroid Hormone Metabolism Support Thyroid hormone conversion - the transformation of inactive T4 (thyroxine) to active T3 (triiodothyronine) - is performed by iodothyronine deiodinase enzymes (DIO1, DIO2, DIO3), which are selenoproteins that depend on the glutathione/thioredoxin antioxidant system for their activity and regeneration

Arentz, S., Abbott, J

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