Common signs of B12 deficiency include fatigue, weakness, pale skin, shortness of breath, numbness or tingling in the hands and feet, difficulty maintaining balance, and cognitive issues like memory problems
Evaluated transdermal delivery of copper tripeptide, demonstrating penetration through skin layers with potential for topical therapeutic applications
Cycle 4 to 6 weeks on, then take a break
This not only enhances patient compliance but also reduces the likelihood of side effects associated with more complex treatment regimens
A 2019 safety review examined 87 human studies on natural astaxanthin including 35 using doses of 12mg per day or higher and found no significant safety concerns or consistent adverse effects.11 Across those trials, approved or studied doses commonly ranged between 2mg and 24mg per day, and higher short-term doses (up to 40mg per day for several weeks) have also shown good tolerability in adults, with no serious events reported
