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Figure 4 shows the mechanism of some of the passive loading and active loading methods in liposomes

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NAMPT mutations 319 enhance NAD + synthesis through other pathways, such as the de novo pathway , upregulate quinolinic acid phosphoribosyltransferase (QAPRT), and enhance amino acid catabolism (for example, tryptophan in the de novo pathway or glutamine in the salvage pathway)