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Acknowledgements We thank Diamond Light Source for beamtime (proposal mx19946), and the staff of beamline I03 for assistance

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Dopamine efflux by MPTP and hydroxyl radical generation

the K i values ( standard deviation) for PAT were 4.86 0.46 nM (TrxR activity) or 7.22 4.96 nM (GR activity), and for OPZ were 18.1 1.1 M (TrxR activity) or 33.8 6.0 M (GR activity)

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