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Abstract This study investigates the interrelationships among drug loading, steric hindrance ( S h ), defined as the spatial constraints imposed by the crystallized polymer network that physically restrict drug crystal growth, effective glass transition temperature ( T g ), and drug particle size in crystalline solid dispersion (CSD) systems

Personnel may come and go, but at a powerful agency like the Food and Drug Administration, individual appointments can have lasting effects on science policy and public trust

*Correspondence: Miriam Kolko, [email protected] This article was submitted to Neurodegeneration, a section of the journal Frontiers in Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Furthermore, researchers value its high selectivity and minimal off-target effects in study models

It really is that simple. According to a recent survey from the health policy research organization KFF, an estimated one in eight adults in the US have used a GLP-1 drug at one point, and nearly half of that number are currently undergoing the process