Cancer cells generate substantial amounts of lactate during aerobic glycolysis, which is expelled into the tumor microenvironment via the monocarboxylate transporter protein (MCT)
The SELECT cardiovascular outcomes trial (N=17,604), published in NEJM 2023 (DOI: 10.1056/NEJMoa2307563), demonstrated a 20% reduction in major adverse cardiovascular events (MACE) -- the composite of cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke -- in overweight or obese adults without diabetes
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However, MCAS can set the stage for a host of chronic conditions such as: environmental and food allergies, asthma, autism, autoimmune, eczema, chronic fatigue syndrome, migraines, chronic pain, fibromyalgia, CIRS, GERD, IBS, infertility, insomnia, mood disorders, multiple chemical sensitivities and even POTS (postural orthostatic tachycardia syndrome)
Researchers have tested it in animals for its regenerative effects