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These include NLRP3 itself, NLRP3-dependent caspase-1 activation, and IL-1 maturation [15]

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7 Pathophysiology Both lymphocytic IBD and lymphocytic neoplasia are often recognized simultaneously in the same cat,40, 84 and numerous authors have suggested that lymphocytic IBD may be a precursor to intestinal lymphoid neoplasia.90, 125 If this is the case, then antigenic factors, such as bacterial population changes or food sensitivities, could be considered primary initiating factors for small cell lymphoma since they are potential underlying etiologies of IBDs