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The second, more sustained phase occurs when nutrients directly contact L-cells in the lower small intestine and colon, producing a more prolonged GLP-1 release that continues for several hours after a meal

Gastrointestinal (GI) side effects of retatrutide are similar to those of semaglutide and other GLP-1 medications

Therapeutic options delaying intestinal glucose delivery or suppressing -cell secretory response have been tried with some success

But after diving into the category, consulting experts, and reviewing research, Ive changed my view

For patients asking is Zepbound covered by insurance or is Wegovy covered by insurance, the answer increasingly is yes, though prior authorization is almost always required