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Their finding marked a decisive breakthrough because it challenged a long-standing belief that nerves controlled the secretion of digestive enzymes that had grown out of the work of Ivan Pavlov, the Russian physiologist who demonstrated that dogs can be conditioned to salivate by the sound of a bell (Rehfeld 2012)
Nahra R, Wang T, Gadde KM, Oscarsson J, Stumvoll M, Jermutus L, Hirshberg B, Ambery P
Thats a problem, both in research and in practice. The drugs work best not as a replacement for healthy habits, he said, but as a tool that makes those habits far more achievable
The skin's barrier prevents these molecules from reaching therapeutic levels in the bloodstream without advanced delivery technology not present in consumer patches