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Keywords : metabolomics, xanthine, glutathione, tamoxifen resistance, xanthine dehydrogenase Breast cancer is the most diagnosed cancer worldwide, with an estimated 2.3 million new cases in 2020 [1]

Enns, GM, Moore, T, Le, A, Atkuri, K, Shah, MK, Cusmano-Ozog, K, Niemi, AK, Cowan, TM 2014, Degree of Glutathione Deficiency and Redox Imbalance Depend on Subtype of Mitochondrial Disease and Clinical Status, The Public Library of Science One , vol

Similarities and differences in the chemical structure of AX compared to other BLs help explain why some patients develop allergy only towards AX and tolerate other BLs (selective reactors) 7,8,9 , whilst others react to several BLs (cross-reactors) 2,8,10,11,12,13

In combination with tyrosine inhibitor even better outcome appeared (140)