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The medication has been structurally modified to resist breakdown by the enzyme dipeptidyl peptidase-4 (DPP-4), which allows it to remain active in the body for an extended period

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After speaking with medical reps and medical science liaisons from Novo Nordisk, Crannage said the semaglutide shortage is expected to last another six months as there is a new manufacturing facility working to catch up with the demand by the end of this year