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These inflammatory responses not only impair testicular tissue, but also directly affect key cells involved in spermatogenesis, including spermatogonia, primary spermatocytes, and Sertoli cells, thereby exacerbating spermatogenesis disorders and leading to reduced sperm count and quality [67, 277]

Genetic and physiological insights into satiation variability predict responses to obesity treatment

Significant increase in water and food intake, variations in the absolute and relative weights of seminal vesicles, and effects noted in urinalysis evaluations were all deemed to be of no toxicological significance because they either represented a physiological response, were temporary and disappeared at the end of the recovery phase, or weren't associated with any microscopic alteration

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