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The current review focuses on Se transport to the brain, including, first of all, selenoprotein P/low-density lipoprotein receptor-related protein 8 (LRP8, also known as apolipoprotein E receptor-2) dependent pathway, and supplementary transport routes of Se into the brain via low molecular weight Se-species
Spinal stenosis, a narrowing of the spinal canal, creates similar compression through a different mechanism
Although they can be given safely as frequently as once a week, we recommend once every 2 to 4 weeks
Claudins create charge-selective channels in the paracellular pathway between epithelial cells
Vehicle selection (liposomes, penetration enhancers) meaningfully affects delivery depth
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