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Conclusion This review highlights the potential role of alogliptin and mechanisms involved in amelioration of several other pathological conditions apart from its role in glucose metabolism
Those who reached higher doses achieved weight loss comparable to trials
However, if the A1c is 60 mg/mmol, or progressive increase in UACR despite appropriate therapy, eGFR 30% increase in serum creatinine within 3 months of starting SGLT2i, ACEi, or ARB, inability to achieve target BP, or signs/symptoms of another underlying kidney disease, such as glomerulonephritis
2025;85:4602-4620.e9
PHDis have also been shown to act on carbohydrate metabolism by activating neoglucogenesis from lactate in the Cori cycle [48]
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