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If symptoms continue or become more severe, minimally invasive procedures or surgery may be recommended

10.21037/qims-23-254 187 LiuH.BaiY.HuangC.WangY.JiY.DuY.et al (2023b)

Assume a tax rate of 20 percent

That same clinical evidence base also shows that these medications don't work equally for every patient, that gastrointestinal side effects are common especially during dose escalation, and that weight tends to return when medication is discontinued without sustained lifestyle changes

Gastrointestinal side effects like nausea and vomiting are most common during the first 2-4 weeks after each dose increase, typically resolving as the body adapts to the new level