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It promotes healing by upregulating growth factors, stimulating angiogenesis (new blood vessel formation), and enhancing collagen synthesis

46 While these single-cell studies significantly deepen our understanding of MuSC heterogeneity and aging trajectories, they do so in dissociated contexts, devoid of spatial relationships

134 By inhibiting cell proliferation and cladogenesis, DHPO exhibits significant antitumor activity in vitro and in vivo

In a 2014 study published in the Journal of Pharmacology and Experimental Therapeutics , Benoist and colleagues used the HGF/c-Met dimerization antagonist Hinge to block Dihexas effects in scopolamine-impaired rats, demonstrating that the procognitive activity requires functional hepatocyte growth factor (HGF) / mesenchymal-epithelial transition factor (c-Met) receptor signaling [3]