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Cell 187(15):38293853 Wolfe MM, Boylan MO, Chin WW (2025) Glucose-dependent insulinotropic polypeptide in incretin physiology: role in health and disease

For many people this is mild and temporary, and they feel like their usual selves within a couple of weeks

The goal is to support overall health, preserve muscle mass, reduce side effects, and ensure youre getting adequate nutrition

For most people taking GLP-1-based therapies including retatrutide gastrointestinal symptoms tend to be most pronounced during the early weeks of treatment and during periods of dose escalation

doi: 10.1002/jnr.21349 137 AdriaenssensAEBiggsEKDarwishTTadrossJSukthankarTGirishMet al