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Phase 2 trials tested doses up to 12mg weekly, though 8mg produced substantial results with more manageable side effects
Nevertheless, long-acting agents such as weekly semaglutide remain clinically relevant because of their prolonged half-lives and continued gastrointestinal effects in some patients
UK Clinical Guide Nausea is one of the most frequently reported side effects when starting Ozempic (semaglutide), affecting approximately 16-20% of patients with type 2 diabetes
Some researchers use semaglutide alongside phentermine , or combine their GLP-1 protocol with other peptides
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